<p>Vidalista 40mg works by inhibiting the action of the PDE5 enzyme, which is responsible for breaking down cyclic guanosine monophosphate (cGMP) in the penile tissues. By inhibiting PDE5, Vidalista allows cGMP to accumulate, promoting relaxation of the smooth muscles in the penis and increasing blood flow, which leads to improved erections when sexually aroused.</p><p>Take Vidalista 40mg about 30 minutes to 1 hour before planned sexual activity. It should be taken with a full glass of water, and it can be taken with or without food. Keep in mind that a high-fat meal may delay the onset of action.</p>